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1

Association of the Host Immune Response with Protection Using a Live Attenuated African Swine Fever Virus Model

Carlson, Jolene, O’Donnell, Vivian, Alfano, Marialexia, Velazquez Salinas, Lauro, Holinka, Lauren, Krug, Peter, Gladue, Douglas, Higgs, Stephen, Borca, Manuel

Journal:

Year:

2016

Language:

english

File:

PDF, 3.27 MB

english, 2016

2

Disorders of Hemoglobin (Genetics, Pathophysiology, and Clinical Management) || Mechanisms and Clinical Complications of Hemolysis in Sickle Cell Disease and Thalassemia

Steinberg, Martin H., Forget, Bernard G., Higgs, Douglas R., Weatherall, David J.

Year:

2009

File:

PDF, 2.73 MB

2009

3

α-thalassaemia

Cornelis L Harteveld, Douglas R Higgs

Journal:

Orphanet Journal of Rare Diseases

Year:

2010

Language:

english

File:

PDF, 3.80 MB

english, 2010

4

Using Genomics to Study How Chromatin Influences Gene Expression

Higgs, Douglas R., Vernimmen, Douglas, Hughes, Jim, Gibbons, Richard

Journal:

Annual Review of Genomics and Human Genetics

Year:

2007

Language:

english

File:

PDF, 683 KB

english, 2007

5

Editorial: US scientists move to combat creationism

Wilkie, Andrew O.M., Higgs, Douglas R.

Journal:

Year:

2008

Language:

english

File:

PDF, 60 KB

english, 2008

6

Postgraduate Haematology (Hoffbrand/Postgraduate) || The Molecular Basis of Haematological Malignancies

Hoffbrand, A Victor, Higgs, Douglas R, Keeling, David M, Mehta, Atul B

Year:

2015

Language:

english

File:

PDF, 960 KB

english, 2015

7

The relationship between genome structure and function

Oudelaar, A. Marieke, Higgs, Douglas R.

Journal:

Nature Reviews Genetics

Year:

2020

File:

PDF, 2.57 MB

2020

8

The ??THAI and ??FIL determinants of ? thalassemia in Taiwan

Higgs, Douglas R., Ayyub, Helena, Chong, Samuel S.

Journal:

American Journal of Hematology

Year:

1999

Language:

english

File:

PDF, 425 KB

english, 1999

9

Molecular–clinical spectrum of the ATR-X syndrome

Richard J. Gibbons, Douglas R. Higgs

Journal:

American Journal of Medical Genetics Part A

Year:

2000

Language:

english

File:

PDF, 317 KB

english, 2000

10

A nonsense mutation of the ATRX gene causing mild mental retardation and epilepsy

Renzo Guerrini, Jennifer L. Shanahan, Romeo Carrozzo, Paolo Bonanni, Douglas R. Higgs, Richard J. Gibbons

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 7.36 MB

english, 2000

11

Co-inheritance of Hb Pak Num Po, a novel α1 gene mutation, and α0 thalassemia associated with transfusion-dependent Hb H disease

Vip Viprakasit, Voravarn S. Tanphaichitr, Gavivann Veerakul, Worrawut Chinchang, Siripan Petrarat, Parichat Pung-Amritt, Douglas R. Higgs

Journal:

American Journal of Hematology

Year:

2004

Language:

english

File:

PDF, 200 KB

english, 2004

12

Population analysis of the alpha hemoglobin stabilizing protein (AHSP) gene identifies sequence variants that alter expression and function

Camila O. dos Santos, Suiping Zhou, Rodrigo Secolin, Xiaomei Wang, Anderson F. Cunha, Douglas R. Higgs, Janet L. Kwiatkowski, Swee Lay Thein, Patrick G. Gallagher, Fernando F. Costa, Mitchell J. Weiss

Journal:

American Journal of Hematology

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

13

X-linked α-thalassemia/mental retardation (ATR-X) syndrome: A new kindred with severe genital anomalies and mild hematologic expression

Elizabeth W. McPherson, Michele M. Clemens, Richard J. Gibbons, Douglas R. Higgs

Journal:

American Journal of Medical Genetics Part A

Year:

1995

Language:

english

File:

PDF, 567 KB

english, 1995

14

Squamous cell carcinoma of the oropharynx : Surgery, radiation therapy, or both

James T. Parsons, William M. Mendenhall, Scott P. Stringer, Robert J. Amdur, Russell W. Hinerman, Douglas B. Villaret, Giselle J. Moore-Higgs, Bruce D. Greene, Tod W. Speer, Nicholas J. Cassisi, Rodne

Journal:

Year:

2002

Language:

english

File:

PDF, 113 KB

english, 2002

15

Explosives sabotage and its investigation in civil aircraft

Douglas Geoffrey Higgs

Journal:

Journal of Occupational Accidents

Year:

1982

Language:

english

File:

PDF, 5.08 MB

english, 1982

16

Hb H hydrops fetalis syndrome associated with the interaction of two common determinants of α thalassaemia (--MED/αTSaudiα)

Vip Viprakasit, Sarah Green, Sue Height, Helena Ayyub, Douglas R. Higgs

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 112 KB

english, 2002

17

De novo deletion within the telomeric region flanking the human α globin locus as a cause of α thalassaemia

Vip Viprakasit, Alexa M. J. Kidd, Helena Ayyub, Sharon Horsley, Jim Hughes, Douglas R. Higgs

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 351 KB

english, 2003

18

Individual specific DNA fingerprints from a hypervariable region probe: alpha-globin 3′HVR

Susan J. Fowler, Peter Gill, David J. Werrett, Douglas R. Higgs

Journal:

Year:

1988

Language:

english

File:

PDF, 905 KB

english, 1988

19

Cumulative trauma disorders: An overview of the problem

V. Leroy Young, Jane Riolo Nemecek, Philip E. Higgs, Douglas J. Ball

Journal:

Journal of Occupational Rehabilitation

Year:

1992

Language:

english

File:

PDF, 1.38 MB

english, 1992

20

Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains

David J. Picketts, Ayse O. Tastan, Douglas R. Higgs, Richard J. Gibbons

Journal:

Mammalian Genome

Year:

1998

Language:

english

File:

PDF, 597 KB

english, 1998

21

Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice

Robert J. Rooney, Rachael R. Daniels, Nancy A. Jenkins, Debra J. Gilbert, Kristen Rothammer, Stephan W. Morris, Douglas R. Higgs, Neal G. Copeland

Journal:

Mammalian Genome

Year:

1998

Language:

english

File:

PDF, 744 KB

english, 1998

22

Are there clinical phenotypes of homozygous sickle cell disease?

Neal Alexander, Douglas Higgs, George Dover, Graham R. Serjeant

Journal:

British Journal of Haematology

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

23

Evidence of genetic heterogeneity in congenital dyserythropoietic anaemia type I

Momin R. Ahmed, Mohamed Zaki, Mohamed A. Sabry, Douglas Higgs, Paresh Vyas, William Wood, Sunitha N. Wickramasinghe

Journal:

British Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 87 KB

english, 2006

24

Prevalence of erythrocyte haemoglobin H inclusions in unselected patients with clonal myeloid disorders

David P. Steensma, Julie C. Porcher, Curtis A. Hanson, Cynthia L. Lathrop, James D. Hoyer, Terra A. Lasho, Ayalew Tefferi, Douglas R. Higgs

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

25

The role of X-inactivation in the gender bias of patients with acquired α-thalassaemia and myelodysplastic syndrome (ATMDS)

Peter S. Haas, Noemi B. A. Roy, Richard J. Gibbons, Marie-Alice Deville, Chris Fisher, Michael Schwabe, Emmanuel Bissé, Alain Van Dorsselaer, Douglas R. Higgs, Michael Lübbert

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

26

Structure and expression of the human [thetas]l globin gene

Hsu, Shih-Lan, Marks, Jon, Shawt, JengPyng, Tam, Ming, Higgs, Douglas R., Shen, Chien Celia, Shen, Che-Kun James

Journal:

Year:

1988

File:

PDF, 358 KB

1988

27

A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n

Wilkie, Andrew O. M., Lamb, Janette, Harris, Peter C., Finney, Roger D., Higgs, Douglas R.

Journal:

Year:

1990

File:

PDF, 767 KB

1990

28

10.1038/35078577

Brown, Karen E., Amoils, Shannon, Horn, Jacqueline M., Buckle, Veronica J., Higgs, Douglas R., Merkenschlager, Matthias, Fisher, Amanda G.

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 234 KB

english, 2001

29

10.1038/74191

Higgs, Douglas R., Gibbons, Richard J., McDowell, Tarra L., Raman, Sundhya, O'Rourke, Delia M., Garrick, David, Ayyub, Helena

Journal:

Nature Genetics

Year:

2000

Language:

english

File:

PDF, 362 KB

english, 2000

30

Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach

Giardine, Belinda, Borg, Joseph, Higgs, Douglas R, Peterson, Kenneth R, Philipsen, Sjaak, Maglott, Donna, Singleton, Belinda K, Anstee, David J, Basak, A Nazli, Clark, Barnaby

Journal:

Nature Genetics

Year:

2011

Language:

english

File:

PDF, 891 KB

english, 2011

31

The relationship between chromosome structure and function at a human telomeric region

Flint, Jonathan, Thomas, Karen, Micklem, Gos, Raynham, Helen, Clark, Kevin, Doggett, Norman A., Andrew, Andrew, Higgs, Douglas R.

Journal:

Nature Genetics

Year:

1997

File:

PDF, 872 KB

1997

32

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease

Tufarelli, Cristina, Stanley, Jackie A Sloane, Garrick, David, Sharpe, Jackie A, Ayyub, Helena, Wood, William G, Higgs, Douglas R

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 1.18 MB

english, 2003

33

Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the α-thalassemia myelodysplasia syndrome (ATMDS)

Gibbons, Richard J, Pellagatti, Andrea, Garrick, David, Wood, William G, Malik, Nicola, Ayyub, Helena, Langford, Cordelia, Boultwood, Jacqueline, Wainscoat, James S, Higgs, Douglas R

Journal:

Nature Genetics

Year:

2003

Language:

english

File:

PDF, 585 KB

english, 2003

34

Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2

Anguita, Eduardo, Hughes, Jim, Heyworth, Clare, Blobel, Gerd A, Wood, William G, Higgs, Douglas R

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 488 KB

english, 2004

35

Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression

Vernimmen, Douglas, Gobbi, Marco De, Sloane-Stanley, Jacqueline A, Wood, William G, Higgs, Douglas R

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 546 KB

english, 2007

36

Understanding erythroid differentiation

Douglas R. Higgs, William G. Wood

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 501 KB

english, 1993

37

Dislocation of Large Diameter Metal-On-Metal Bearings: An Indicator of Metal Reaction?

Bipin Theruvil, Nijil Vasukutty, Nick Hancock, David Higgs, Douglas G. Dunlop, Jeremy M. Latham

Journal:

The Journal of Arthroplasty

Year:

2011

Language:

english

File:

PDF, 604 KB

english, 2011

38

Disordered eating behaviour is associated with blunted cortisol and cardiovascular reactions to acute psychological stress

Annie T. Ginty, Anna C. Phillips, Suzanne Higgs, Jennifer L.J. Heaney, Douglas Carroll

Journal:

Psychoneuroendocrinology

Year:

2012

Language:

english

File:

PDF, 400 KB

english, 2012

39

Localization, expression and genomic structure of the gene encoding the human serine protease testisin

John D. Hooper, Natalie Bowen, Heidi Marshall, Lara M. Cullen, Raman Sood, Rachael Daniels, Melanie A. Stuttgen, John F. Normyle, Douglas R. Higgs, Daniel L. Kastner, Steven M. Ogbourne, Martin F. Per

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2000

Language:

english

File:

PDF, 640 KB

english, 2000

40

2 The regulation of human globin gene expression

Frank Grosveld, Niall Dillon, Douglas Higgs

Journal:

Baillière's Clinical Haematology

Year:

1993

Language:

english

File:

PDF, 2.25 MB

english, 1993

41

5 α-Thalassaemia

Douglas R. Higgs

Journal:

Baillière's Clinical Haematology

Year:

1993

Language:

english

File:

PDF, 4.10 MB

english, 1993

42

The haematology of homozygous sickle cell disease after the age of 40 years

Joanne Morris, David Dunn, Marjorie Beckford, Yvonne Grandison, Karlene Mason, Douglas Higgs, Karel De Ceulaer, Beryl Serjeant, Graham Serjeant

Journal:

British Journal of Haematology

Year:

1991

Language:

english

File:

PDF, 366 KB

english, 1991

43

A base substitution (T→C) in codon 29 of the α2-globin gene causes α thalassaemia

Georgina W. Hall, Swee Lay Thein, Adrian C. Newland, Morag Chisholm, Jan Traeger-Synodinos, E. Kanavakis, C. Kattamis, Douglas R. Higgs

Journal:

British Journal of Haematology

Year:

1993

Language:

english

File:

PDF, 884 KB

english, 1993

44

The red cell distribution width in sickle cell disease—is it of clinical value?

MINERVA THAME, YVONNE GRANDISON, KARLENE MASON, MARVIN THOMPSON, DOUGLAS HIGGS, JOANNE MORRIS, BERYL SERJEANT, GRAHAM SERJEANT

Journal:

International Journal of Laboratory Hematology (Blackwell)

Year:

1991

Language:

english

File:

PDF, 430 KB

english, 1991

45

Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia

David P. Steensma, Richard J. Gibbons, Ruben A. Mesa, Ayalew Tefferi, Douglas R. Higgs

Journal:

European Journal of Haematology

Year:

2005

Language:

english

File:

PDF, 187 KB

english, 2005

46

A novel mutation in the last exon of ATRX in a patient with α-thalassemia myelodysplastic syndrome

Daniel B. Costa, Christopher A. Fisher, Kenneth B. Miller, German A. Pihan, David P. Steensma, Richard J. Gibbons, Douglas R. Higgs

Journal:

European Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 263 KB

english, 2006

47

5-Azacytidine treatment of the patient with ATMDS

Daniel B. Costa, Christopher A. Fisher, Kenneth B. Miller, German A. Pihan, David P. Steensma, Richard J. Gibbons, Douglas R. Higgs

Journal:

European Journal of Haematology

Year:

2006

Language:

english

File:

PDF, 47 KB

english, 2006

48

Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer – a phase II study

Shannon K Tomlinson, Susan A Melin, Vetta Higgs, Douglas R White, Paul Savage, Douglas Case, A William Blackstock

Journal:

Year:

2002

Language:

english

File:

PDF, 320 KB

english, 2002

49

Molecular biology: RNA discrimination

Kowalczyk, Monika S., Higgs, Douglas R., Gingeras, Thomas R.

Journal:

Year:

2012

Language:

english

File:

PDF, 426 KB

english, 2012

50

Conservation of Position and Sequence of a Novel, Widely Expressed Gene Containing the Major Human α-Globin Regulatory Element

PARESH VYAS, MARK A. VICKERS, DAVID J. PICKETTS, DOUGLAS R. HIGGS

Journal:

Year:

1995

Language:

english

File:

PDF, 684 KB

english, 1995